Protein Structure

X-ray crystallography
By taking advantage of the Shanghai Synchrotron Radiation Facility (SSRF) and National Center for Protein Science Shanghai (NCPPS), the Structural Biology group provides services for high-quality crystal production, X-ray diffraction data collection, and structure determination. They are able to provide high quality support for a variety of different type of project:
- Fragment / Structure Based Drug Design (FBDD/SBDD)
- Antibody structural studies to support IP and/or design
- Lipidic Cubic Phase (LCP) crystallization services
- DNA to Structure
Nuclear Magnetic Resonance (NMR)
The close collaboration with our Chemistry Department and National for Protein Science Shanghai (NCPSS) enables the Structural Biology Group to provide start providing services using NMR technology.
- Membrane protein production to support GPCR drug discovery
- Isotope-labeled protein production to support NMR services

Biophysics study
- Surface Plasmon Resonance (SPR)
- Thermal Shift Assay (TSA)
- Dynamic Light Scattering (DLS)
- Service Overview
- Discovery Chemistry
- Biology & Pharmacology
- DMPK / Exploratory Toxicology
- Biologics Discovery
- Biologics CMC
- Small Molecule CMC