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Biology & Pharmacology

Home Biology & Pharmacology

Biology & Pharmacology

Started in 2007, ChemPartner’s Biology department specializes in drug discovery services for several key Bio-therapeutic areas: oncology, cell biology, tumor immunology, immunology/inflammation,neuroscience/metabolic disorders, histology/pathology . Our In Vitro Pharmacology team supports studies by running the hundreds of necessary assays for biology studies. Our Biology team is led by senior staff members with extensive discovery experience in the biopharmaceutical industry in the US and Europe.

We pride ourselves on having numerous validated key discovery assays and assay panels for many different targets (e.g. extensive cancer cell panel (700+), epigenetic enzyme panel, kinase panels,hERG QPatch). Many are routinely used and customized in vivo models like patients-derived xenografts, cancer cell-derived xenografts, syngeneic models, along with many CNS-related (5XFAD mice), or metabolic disease-related (e.g. Ob/Ob, db/db mice) transgenic rodent models are being run in an AAALAC approved, state-of-the-art animal housing and breeding facility.

Our highly experienced and communicative biologists provide strong intellectual input when working closely and flexibly with our clients. We provide customized designs or co-develop many of the needed in vitro & in vivo assays and disease models required to drive all discovery projects within a tight timeline. Furthermore, we are well-equipped with the latest technology platforms needed including Caliper, FACS, Luminex, Laborus, and QPatch.

Our well-coordinated, integrative services model means our medicinal chemists, DMPK, and bioanalytical scientist colleagues are all working together on the same campus. We have efficiently and successfully delivered many leads and clinical candidates with several of them currently in clinical trials.

Our Services:

  • Oncology
  • Pathology Core Facility
  • Immunology
  • Tumor Immunology
  • Neuroscience
  • Cell Biology
  • In Vitro Biology
  • Metabolic & Cardiovascular Diseases
  • Epigenetics
  • Service Overview
  • Discovery Chemistry
    • Synthetic Chemistry
    • Medicinal Chemistry
    • Library Chemistry
    • Peptide Chemistry
    • Fragment Based Screening
    • Computer Aided Drug Design
    • Analytical Services
    • Protein Structure
  • Biology & Pharmacology
    • Oncology
      • OncoCP Database
    • Pathology Core Facility
      • Histopathology
      • Molecular Pathology
    • Immunology
      • Primary immune cell assays
      • Immune cell line assays
      • Autoimmune disease models
      • In vivo PD models
      • Immune profiling for MOA
    • Tumor Immunology
    • Neuroscience
      • Volume Discount Fast services for Neuroscience
      • Behavioral Pharmacology
      • In vivo Pain Models
      • Non-Human Primate Cognition
      • In Vitro Electrophysiology
    • Cell Biology
      • Target Validation
      • Cell-based Assays
      • Cancer Cell Line Panel Screen
      • Biomarker Analysis
    • In Vitro Biology
      • Kinases
      • Epigenetics
      • GPCR, NR, Ion-channel, Transporter
      • Ubiquitin & PROTAC
      • KRAS
      • COVID-19
      • Radiometric
      • Customized assay development
      • High throughput screening
      • MOA Study
    • Metabolic & Cardiovascular Diseases
  • DMPK / Exploratory Toxicology
    • DMPK / Exploratory Toxicology
      • In vitro ADME
      • Pharmacokinetics
      • Exploratory Toxicology
      • Bioanalysis
      • Regulatory filing
    • Biomarkers, Preclinical & Clinical Sample Bioanalysis
    • Large molecule PK/BA services
      • Monoclonal Antibodies
      • Antibody Drug Conjugates
      • Bispecific Antibodies
      • Proteins & Peptides
      • Immunogenicity
  • Biologics Discovery
    • Antibody Discovery
      • Hybridoma
      • Antibody Engineering
      • Phage Display
      • Antibody-Drug Conjugate
    • Protein Science
    • Biologics Analytical Services
      • mAb Release Tests and Extended Characterization
      • Antibody-Drug Conjugate(ADC) Analysis
      • Therapeutic Protein Characterization
      • Biomolecular Interaction Analysis
    • B Cell Cloning
  • Biologics CMC
    • Stable Cell Line Development
    • Process Development
    • Formulation Development
    • Aseptic Filling and Freeze-drying
    • Drug Developability / Manufacturability study
    • Final Container Extractables & Leachables Study
    • Analytical Development and Testing
    • GMP Production
  • Small Molecule CMC
    • Process R&D Services
    • Process Safety
    • Analytical Development
    • Pre-Formulation Development
    • Formulation Development
    • ICH Stability Studies
    • CMC CTD Support
    • Manufacturing

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